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Article

Opposing role of condensin hinge against replication protein A in mitosis and interphase through promoting DNA annealing.

Open biology - 1 Dec 2011

Akai Yuko, Kurokawa Yumiko, Nakazawa Norihiko, Tonami-Murakami Yuko, Suzuki Yuki, Yoshimura Shige H, Iwasaki Hiroshi, Shiroiwa Yoshiharu, Nakamura Takahiro, Shibata Eri, Yanagida Mitsuhiro

Abstract excerpt

Condensin is required for chromosome dynamics and diverse DNA metabolism. How condensin works, however, is not well understood. Condensin contains two structural maintenance of chromosomes (SMC) subunits with the terminal globular domains connected to coiled-coil that is interrupted by the central hinge. Heterotrimeric non-SMC subunits regulate SMC. We identified a novel fission yeast SMC hinge mutant, cut14-Y1,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22645654
DOI: 10.1098/rsob.110023
PMCID: PMC3352087

Genes

SMC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Opposing role of condensin hinge against replication protein A in mitosis and interphase through promoting DNA annealing.PMID 22645654Read ↗

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