Article
Low-MBL producing genotypes playing a role on protection to leprosy and its multibacillary forms in a highly endemic area for leprosy in Brazil
2022-08-25
Abstract excerpt
The high frequency of MBL2 mutant alleles found in various human populations suggests that they provide some selective advantage. One of the hypotheses is that MBL deficiency may be protective against intracellular pathogens, including Mycobacterium leprae . In this study, we investigated the role of MBL2 in the susceptibility to leprosy. Single-nucleotide variants (SNV) B (rs1800450) and C (rs1800451) in exon 1 o...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 684893a0-0c0f-5303-a693-0aad444bc5eb
- DOI
- 10.1101/2022.08.22.22279041