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Article

Inhibition of Small Maf Function in Pancreatic β-Cells Improves Glucose Tolerance Through the Enhancement of Insulin Gene Transcription and Insulin Secretion.

Endocrinology - 1 Oct 2015

Nomoto Hiroshi, Kondo Takuma, Miyoshi Hideaki, Nakamura Akinobu, Hida Yoko, Yamashita Ken-ichiro, Sharma Arun J, Atsumi Tatsuya

Abstract excerpt

The large-Maf transcription factor v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (MafA) has been found to be crucial for insulin transcription and synthesis and for pancreatic β-cell function and maturation. However, insights about the effects of small Maf factors on β-cells are limited. Our goal was to elucidate the function of small-Maf factors on β-cells using an animal model of endogenous small-Maf...

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Identifiers

PMID: 25763640
DOI: 10.1210/en.2014-1906
PMCID: PMC4588816

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Inhibition of Small Maf Function in Pancreatic β-Cells Improves Glucose Tolerance Through the Enhancement of Insulin Gene Transcription and Insulin Secretion.PMID 25763640Read ↗

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