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MafA Regulation in β-Cells: From Transcriptional to Post-Translational Mechanisms

31 Mar 2022

Abstract excerpt

β-cells are insulin-producing cells in the pancreas that maintain euglycemic conditions. Pancreatic β-cell maturity and function are regulated by a variety of transcription factors that enable the adequate expression of the cellular machinery involved in nutrient sensing and commensurate insulin secretion. One of the key factors in this regulation is MAF bZIP transcription factor A (MafA). MafA expression is...

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PMID: 35454124
DOI: 10.3390/biom12040535

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