Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of PD-L1 gene polymorphisms and circulating sPD-L1 levels with HBV infection susceptibility and related liver disease progression.

Gene - 5 Jan 2022

Xuan Hoan Nghiem, Thi Minh Huyen Pham, Dinh Tung Bui, Phuong Giang Dao, Tat Trung Ngo, Tien Sy Bui, Thi Tuan Nguyen, Thi Ngoc Dung Dang, Reddy Pallerla Srinivas, Velavan Thirumalaisamy P, Hong Bang Mai, Huu Song Le

Abstract excerpt

Soluble molecules of programmed death ligand 1 (sPD-L1) are known to modulate T-cell depletion, an important mechanism of hepatitis B virus (HBV) persistence and liver disease progression. In addition, PD-L1 polymorphisms in the 3'-UTR can influence PD-L1 expression and have been associated with cancer risk, although not definitively. The purpose of this study was to investigate the association of PD-L1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to B7-H1 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Hepatocellular

Share to Hepatitis B, Chronic

Share to Hepatitis B virus

Share to Liver Cirrhosis

Share to Liver Neoplasms

Share to Predictive Value of Tests

Source

Identifiers

PMID: 34478821
DOI: 10.1016/j.gene.2021.145935

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of PD-L1 gene polymorphisms and circulating sPD-L1 levels with HBV infection susceptibility and related liver disease progression.PMID 34478821Read ↗

Circulating level of sPD-1 and PD-1 genetic variants are associated with hepatitis B infection and related liver disease progression.Semantic proximity Read ↗

Plasma levels of sPD-1 and PD-1 genetic variants are associated with hepatitis B infection and related liver disease progressionSemantic proximity Read ↗

[Association of circulating levels of soluble PD-1, PD-1 gene polymorphisms with HBV infection and HBV infection-associated hepatocellular carcinoma].Semantic proximity Read ↗

Genetic variants of programmed cell death 1 are associated with HBV infection and liver disease progression.Semantic proximity Read ↗

PD-1 mRNA expression is associated with clinical and viral profile and PD1 3'-untranslated region polymorphism in patients with chronic HBV infection.Semantic proximity Read ↗

Programmed death-ligand 1 (PD-L1) polymorphisms as predictive biomarkers for the development of liver cirrhosis and hepatocellular carcinoma in HCV Egyptian patients.Semantic proximity Read ↗

A Programmed Cell Death-1 Haplotype is Associated with Clearance of Hepatitis B Virus.Semantic proximity Read ↗

Association of rs10204525 genotype GG and rs2227982 CC combination in programmed cell death 1 with hepatitis B virus infection riskSemantic proximity Read ↗

Interaction between HBsAg response and the prognosis of patients with HBV-associated HCC receiving anti-PD-1/PD-L1Semantic proximity Read ↗

Relationship between programmed cell death-1 polymorphisms and clearance of hepatitis B virus.Semantic proximity Read ↗

microRNA-4717 differentially interacts with its polymorphic target in the PD1 3' untranslated region: A mechanism for regulating PD-1 expression and function in HBV-associated liver diseases.Semantic proximity Read ↗

Genome-wide association study identifies new loci associated with risk of HBV infection and disease progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.