Programmed cell death-1 3'-untranslated region polymorphism is associated with spontaneous clearance of hepatitis B virus infection.

doi:10.1002/jmv.25265

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Article

Programmed cell death-1 3'-untranslated region polymorphism is associated with spontaneous clearance of hepatitis B virus infection.

Journal of medical virology - 1 Nov 2018

Chihab Hajar, Jadid Fatima-Zahra, Foka Pelagia, Zaidane Imane, El Fihry Raouia, Georgopoulou Urania, Marchio Agnes, Elhabazi Abdellah, Chair Mohammed, Pineau Pascal, Ezzikouri Sayeh, Benjelloun Soumaya

Abstract excerpt

Hepatitis B virus (HBV)-specific CD8+ T cells play an important role in the clearance of HBV infection. Programmed cell death-1 (PD-1), an immunosuppressive molecule that regulates T-cell activation and peripheral immune tolerance, is increasingly shown to influence the outcome of HBV infection. rs10204525, a single-nucleotide polymorphism in the 3'-untranslated region (3'-UTR) of PD-1, has been associated with...

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PMID: 30016557
DOI: 10.1002/jmv.25265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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