Article
A quantitative association study between schizotypal traits and COMT, PRODH and BDNF genes in a healthy Chinese population.
Psychiatry research - 30 Sept 2007
Ma Xiaohong, Sun Jinhua, Yao Jing, Wang Qiang, Hu Xun, Deng Wei, Sun Xueli, Liu Xiehe, Murray Robin M, Collier David A, Li Tao
Abstract excerpt
Previous studies have suggested that catechol-O-methyltransferase (COMT), proline dehydrogenase (PRODH), and brain-derived neurotrophic factor (BDNF) genes are possible susceptibility genes for schizophrenia. We hypothesized that these genes are also associated with schizotypal traits, which are heritable and related to schizophrenia. We genotyped five single nucleotide polymorphism (SNPs) from the COMT, PRODH...
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