Article
Higher scores of self reported schizotypy in healthy young males carrying the COMT high activity allele.
Molecular psychiatry - 1 Jan 2002
Avramopoulos D, Stefanis N C, Hantoumi I, Smyrnis N, Evdokimidis I, Stefanis C N
Abstract excerpt
The gene for COMT is located on chromosome 22q11, an area that has been implicated in the pathogenesis of schizophrenia through linkage studies and through the detection of deletions in schizophrenics and velocardiofacial syndrome patients that often present psychotic symptomatology. Additionally catechol-O-methyl transferase activity has been found increased in schizophrenia and a functional polymorphism in the...
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