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Article

Sex-specific association between schizophrenia polygenic risk and subclinical schizophrenia-related traits.

Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2025

Mas-Bermejo Patricia, Papiol Sergi, Torrecilla Pilar, Lavín Valeria, Kwapil Thomas R, Barrantes-Vidal Neus, Rosa Araceli

Abstract excerpt

BACKGROUND: According to the dimensional view of psychiatric disorders, psychosis is expressed as a continuum in the general population. However, the investigation of the putative genetic aetiological continuity between its clinical and subclinical phenotypes has yielded mixed results. We aimed to replicate previous findings regarding the association of polygenic risk for schizophrenia with subclinical traits...

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PMID: 39368539
DOI: 10.1016/j.pnpbp.2024.111161

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