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Article

Establishment and phenotypic analysis of an Mstn knockout rat.

Biochemical and biophysical research communications - 12 Aug 2016

Gu Hao, Cao Yong, Qiu Bin, Zhou Zhiqiang, Deng Ran, Chen Zhuang, Li Rongfeng, Li Xueling, Wei Qiang, Xia Xianzhu, Yong Weidong

Abstract excerpt

Myostatin (Mstn) is an inhibitor of myogenesis, regulating the number and size of skeletal myocytes. In addition to its myogenic regulatory function, Mstn plays important roles in the development of adipose tissues and in metabolism. In the present study, an Mstn knockout rat model was generated using the zinc finger nuclease (ZFN) technique in order to further investigate the function and mechanism of Mstn in...

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Identifiers

PMID: 27289021
DOI: 10.1016/j.bbrc.2016.06.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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