Article
Analysis of variants and mutations in the human winged helix FOXA3 gene and associations with metabolic traits.
International journal of obesity (2005) - 1 Jun 2015
Adler-Wailes D C, Alberobello A T, Ma X, Hugendubler L, Stern E A, Mou Z, Han J C, Kim P W, Sumner A E, Yanovski J A, Mueller E
Abstract excerpt
BACKGROUND/OBJECTIVES: The forkhead factor Foxa3 is involved in the early transcriptional events controlling adipocyte differentiation and plays a critical function in fat depot expansion in response to high-fat diet regimens and during aging in mice. No studies to date have assessed the potential associations of genetic variants in FOXA3 with human metabolic outcomes. SUBJECTS/METHODS: In this study, we...
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