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Article

Role of forkhead box protein A3 in age-associated metabolic decline

15 Sept 2014

Abstract excerpt

Aging is associated with increased adiposity and diminished thermogenesis, but the critical transcription factors influencing these metabolic changes late in life are poorly understood. We recently demonstrated that the winged helix factor forkhead box protein A3 (Foxa3) regulates the expansion of visceral adipose tissue in high-fat diet regimens; however, whether Foxa3 also contributes to the increase in...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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Share to Genetics, Aging, and Longevity in Model Organisms

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PMID: 25225406
DOI: 10.1073/pnas.1407640111

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