Article

Fine-Scale Haplotype Mapping Reveals Association of Fto Gene with Osteoporosis and Fracture Risk in Postmenopausal Women

2024-07-25

Abstract excerpt

<h4>Introduction: </h4> The Fat Mass and Obesity-Associated (FTO) gene encodes a demethylase that modulates RNA N6-methyladenosine (m6A) playing a regulatory role in adipocyte differentiation and pathogenesis of human obesity. Methods. To understand the potential role of FTO in osteoporosis (OP) we investigated five single nucleotide variations (SNVs) in intron 1 (rs8057044, rs8050136, rs9939609, rs62033406, rs993...

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Literature Corpus work: 6162b8be-1feb-550d-bc11-f688c83a6467
DOI: 10.20944/preprints202407.1993.v1

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