Article
Genetics of rheumatoid arthritis in Asia--present and future.
Nature reviews. Rheumatology - 1 Jun 2015
Yamamoto Kazuhiko, Okada Yukinori, Suzuki Akari, Kochi Yuta
Abstract excerpt
Genome-wide association studies (GWAS) have uncovered numerous susceptibility genes for rheumatoid arthritis (RA) in patients of European, Asian and other ethnic ancestries. Although previous transethnic GWAS meta-analyses enabled the identification of several novel loci, the genetic heterogeneity observed in the PADI4 and PTPN22 genes suggests that ethnic variation should be considered. In addition, the effects...
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