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Article

Update on the genetic architecture of rheumatoid arthritis.

Nature reviews. Rheumatology - 1 Jan 2017

Kim Kwangwoo, Bang So-Young, Lee Hye-Soon, Bae Sang-Cheol

Abstract excerpt

Human genetic studies into rheumatoid arthritis (RA) have uncovered more than 100 genetic loci associated with susceptibility to RA and have refined the RA-association model for HLA variants. The majority of RA-risk variants are highly shared across multiple ancestral populations and are located in noncoding elements that might have allele-specific regulatory effects in relevant tissues. Emerging multi-omics...

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PMID: 27811914
DOI: 10.1038/nrrheum.2016.176

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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