Article
Genetics of rheumatoid arthritis.
Seminars in immunopathology - 1 Jan 2022
Padyukov Leonid
Abstract excerpt
Rheumatoid arthritis (RA) is an inflammatory autoimmune disease involving symmetric joints and is generally characterized by persistent pain, tenderness, and destruction of joints. The vast majority of RA patients produce autoantibodies, and immune cell involvement in disease development is well recognized, as is the contribution of other types of cells in synovial tissue, like fibroblasts. It is known that there...
Topics
- Alleles
- Arthritis, Rheumatoid
- Autoantibodies
- Genetic Predisposition to Disease
- HLA-DRB1 Chains
- Humans
- Proteomics