Article
Ethnogenetic heterogeneity of rheumatoid arthritis-implications for pathogenesis.
Nature reviews. Rheumatology - 1 May 2010
Kochi Yuta, Suzuki Akari, Yamada Ryo, Yamamoto Kazuhiko
Abstract excerpt
Autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus are generally considered multifactorial-that is, they involve both genetic and environmental factors. Technical advances in human genetics over the past 5 years have enabled the survey of the entire human genome for disease susceptibility genes and have contributed to a greater understanding of the molecular mechanisms underlying...
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