Genetics of rheumatoid arthritis: underlying evidence of ethnic differences.

doi:10.1016/j.jaut.2009.02.020

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Article

Genetics of rheumatoid arthritis: underlying evidence of ethnic differences.

Journal of autoimmunity - 1 Jan 2000

Kochi Yuta, Suzuki Akari, Yamada Ryo, Yamamoto Kazuhiko

Abstract excerpt

A new age has begun in the genetics of rheumatoid arthritis (RA), as genome-wide association studies scanning the human genome have been put into practical use. Among the RA-susceptibility genes identified by genetic studies, HLA-DRB1 gene appears to represent the most major determinant of genetic predisposition to RA. However, inconsistent results of the contributions of non-HLA susceptibility genes have been...

Topics

Antigens, CD
Arthritis, Rheumatoid
Genetic Predisposition to Disease
Genome-Wide Association Study
HLA-DR Antigens
HLA-DRB1 Chains
Humans
Hydrolases
Polymorphism, Genetic
Protein Tyrosine Phosphatase, Non-Receptor Type 22
Protein-Arginine Deiminase Type 4
Protein-Arginine Deiminases
Receptors, Immunologic
Signaling Lymphocytic Activation Molecule Family

Source

Open in PubMed

Identifiers

PMID: 19324521
DOI: 10.1016/j.jaut.2009.02.020

Genes

PADI4
FCRL3
PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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