Article
Genetics and epigenetics of rheumatoid arthritis.
Nature reviews. Rheumatology - 1 Mar 2013
Viatte Sebastien, Plant Darren, Raychaudhuri Soumya
Abstract excerpt
Investigators have made key advances in rheumatoid arthritis (RA) genetics in the past 10 years. Although genetic studies have had limited influence on clinical practice and drug discovery, they are currently generating testable hypotheses to explain disease pathogenesis. Firstly, we review here the major advances in identifying RA genetic susceptibility markers both within and outside of the MHC. Understanding...
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