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Article

CXCR3 in carcinoma progression.

1 Jul 2015

Abstract excerpt

CXCR3 is a G-protein coupled receptor which binds to ELR-negative CXC chemokines that have been found to impact immune responses, vascular develop, and wound repair. More recently, CXCR3 has been examined in the context of cancer and increased expression in many human tumors has been correlated with poor prognosis in breast, melanoma, colon and renal cancer patients. Three variants of CXCR3 are identified so far...

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PMID: 25663474
DOI: 10.14670/hh-11-594

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