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Article

CXCL12-CXCR4/CXCR7 Axis in Cancer: from Mechanisms to Clinical Applications

1 Jan 2023

Abstract excerpt

Cancer is a multi-step disease caused by the accumulation of genetic mutations and/or epigenetic changes, and is the biggest challenge around the world. Cytokines, including chemokines, exhibit expression changes and disorders in all human cancers. These cytokine abnormalities can disrupt homeostasis and immune function, and make outstanding contributions to various stages of cancer development such as invasion,...

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PMID: 37497001
DOI: 10.7150/ijbs.82317

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