Article

The Dual Roles of the CXCL10-CXCR3 Axis and Its Therapeutic Potential in Osteosarcoma

2024-06-06

Abstract excerpt

<h4>ABSTRACT</h4> The CXCL10-CXCR3 axis is recognized for its dual role in tumor biology, promoting tumor growth and metastasis via autocrine signaling while also eliciting anti-tumor responses through paracrine signaling. However, its specific functions in osteosarcoma (OS), the most prevalent malignant bone tumor in children, remain poorly understood. Our previous research has demonstrated that elevated circula...

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Literature Corpus work: 3d0e5b42-b590-5942-b0ff-6926c8b25430
DOI: 10.1101/2024.06.04.597467

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