Article

Activation of the Chemokine Receptor 3 Pathway Leads to a Better Response to Immune Checkpoint Inhibitors in Patients with Metastatic Urothelial Carcinoma

2022-03-07

Abstract excerpt

Immune checkpoint inhibitors (ICIs) have made important breakthrough in anti-tumor therapy, however, no single biomarker can accurately predict their efficacy. Studies have found that tumor microenvironment is a key factor for determining the response to ICI therapy. Cytokine receptor 3 (C-X-C Motif Chemokine Receptor 3, CXCR3) pathway has been reported to play an important role in the migration, activation, and r...

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Literature Corpus work: 64af403c-8e5a-5bc7-bb4d-70e0bd82b398
DOI: 10.21203/rs.3.rs-1403950/v1

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