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Article

Behavioral changes following a single episode of early-life seizures support the latent development of an autistic phenotype.

Epilepsy & behavior : E&B - 1 Mar 2015

Bernard Paul B, Castano Anna M, Beitzel Christy S, Carlson Vivian B, Benke Tim A

Abstract excerpt

We probed the developmental and behavioral consequences of a single episode of kainic acid-induced early-life seizures (KA-ELS) in the rat on postnatal day 7. Correlates of developmental trajectory were not altered, demonstrating that long-term consequences following KA-ELS are not initiated by secondary causes, such as malnourishment or alterations in maternal care. We report reduced marble burying in adult...

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Identifiers

PMID: 25659043
DOI: 10.1016/j.yebeh.2015.01.006
PMCID: PMC4405461

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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