Article
Elevated anxiety and depressive-like behavior in a rat model of genetic generalized epilepsy suggesting common causation.
Experimental neurology - 1 Jan 2008
Jones Nigel C, Salzberg Michael R, Kumar Gaurav, Couper Abbie, Morris Margaret J, O'Brien Terence J
Abstract excerpt
The explanation for the increased prevalence of neuropsychiatric disorders in epilepsy patients is uncertain, with both biological and psychosocial factors proposed. Increasing evidence supports the idea of shared neurobiological processes leading both to seizures and to behavioral, emotional and cognitive disturbance. This study addresses this using Genetic Absence Epilepsy Rats from Strasbourg (GAERS), a model...
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