Article
Genetic ablation of metabotropic glutamate receptor 5 in rats results in an autism-like behavioral phenotype.
PloS one - 1 Jan 2022
Eshraghi Adrien A, Memis Idil, Wang Florence, White Isaiah, Furar Emily, Mittal Jeenu, Moosa Moeed, Atkins Coleen M, Mittal Rahul
Abstract excerpt
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in communication, and social skills, as well as repetitive and/or restrictive interests and behaviors. The severity of ASD varies from mild to severe, drastically interfering with the quality of life of affected individuals. The current occurrence of ASD in the United States is about 1 in 44 children. The precise...
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