Article
A genetic epilepsy rat model displays endophenotypes of psychosis.
Neurobiology of disease - 1 Jul 2010
Jones Nigel C, Martin Sally, Megatia Ika, Hakami Tahir, Salzberg Michael R, Pinault Didier, Morris Margaret J, O'Brien Terence J, van den Buuse Maarten
Abstract excerpt
The incidence of psychosis is increased in people with epilepsy, including idiopathic generalized epilepsies. To study the biological basis for this co-morbidity, we compared GAERS, a genetic rat model of absence epilepsy, to non-epileptic control rats (NEC). Mature, 14-week old GAERS showed enha...
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