Article
Seizure expression, behavior, and brain morphology differences in colonies of Genetic Absence Epilepsy Rats from Strasbourg.
Epilepsia - 1 Dec 2014
Powell Kim L, Tang Howard, Ng Caroline, Guillemain Isabelle, Dieuset Gabriel, Dezsi Gabi, Çarçak Nihan, Onat Filiz, Martin Benoît, O'Brien Terence J, Depaulis Antoine, Jones Nigel C
Abstract excerpt
OBJECTIVE: Originally derived from a Wistar rat strain, a proportion of which displayed spontaneous absence-type seizures, Genetic Absence Epilepsy Rats from Strasbourg (GAERS) represent the most widely utilized animal model of genetic generalized epilepsy. Here we compare the seizure, behavioral, and brain morphometric characteristics of four main GAERS colonies that are being actively studied internationally:...
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