Article
The EL mouse: a natural model of autism and epilepsy.
Epilepsia - 1 Feb 2011
Meidenbauer Joshua J, Mantis John G, Seyfried Thomas N
Abstract excerpt
PURPOSE: Autism is a multifactorial disorder that involves impairments in social interactions and communication, as well as restricted and repetitive behaviors. About 30% of individuals with autism develop epilepsy by adulthood. The EL mouse has long been studied as a natural model of multifactorial idiopathic generalized epilepsy with complex partial seizures. Because epilepsy is a comorbid trait of autism, we...
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