Article
Seizure-prone EL/Suz mice exhibit physical and motor delays and heightened locomotor activity in response to novelty during development.
Epilepsy & behavior : E&B - 1 May 2005
McFadyen-Leussis Melanie P, Heinrichs Stephen C
Abstract excerpt
Seizure-prone EL/Suz mice have been studied as a model of multifactorial epilepsy for five decades. In prior behavioral studies, EL/Suz mice were shown to exhibit heightened locomotor activity, which implies a state of underlying hyperexcitability. The aim of the present study was to establish the premorbid behavioral development of basic motor skills and activity levels of EL/Suz mice, as compared with DDY mice,...
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