Article
Repetitive behaviors in the Shank1 knockout mouse model for autism spectrum disorder: developmental aspects and effects of social context.
Journal of neuroscience methods - 30 Aug 2014
Sungur A Özge, Vörckel Karl J, Schwarting Rainer K W, Wöhr Markus
Abstract excerpt
BACKGROUND: Autism spectrum disorder (ASD) is characterized by persistent deficits in social behavior and communication, together with restricted and repetitive patterns of behavior. Several ASD candidate genes have been identified, including the SHANK gene family with its three family members SHANK1, SHANK2, and SHANK3. METHODS: Typically, repetitive behavior in mouse models for ASD is assessed by measuring...
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