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Article

Different nucleosomal architectures at early and late replicating origins in Saccharomyces cerevisiae.

BMC genomics - 13 Sept 2014

Soriano Ignacio, Morafraile Esther C, Vázquez Enrique, Antequera Francisco, Segurado Mónica

Abstract excerpt

BACKGROUND: Eukaryotic genomes are replicated during S phase according to a temporal program. Several determinants control the timing of origin firing, including the chromatin environment and epigenetic modifications. However, how chromatin structure influences the timing of the activation of specific origins is still poorly understood. RESULTS: By performing high-resolution analysis of genome-wide nucleosome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25218085
DOI: 10.1186/1471-2164-15-791
PMCID: PMC4176565

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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