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Article

PIK3CA mutations predict recurrence in localized microsatellite stable colon cancer.

Cancer medicine - 1 Mar 2015

Manceau Gilles, Marisa Laetitia, Boige Valérie, Duval Alex, Gaub Marie-Pierre, Milano Gérard, Selves Janick, Olschwang Sylviane, Jooste Valérie, le Legrain Michè, Lecorre Delphine, Guenot Dominique, Etienne-Grimaldi Marie-Christine, Kirzin Sylvain, Martin Laurent, Lepage Come, Bouvier Anne-Marie, Laurent-Puig Pierre

Abstract excerpt

PIK3CA, which encodes the p110α catalytic subunit of PI3Kα, is one of the most frequently altered oncogenes in colon cancer (CC), but its prognostic value is still a matter of debate. Few reports have addressed the association between PIK3CA mutations and survival and their results are controversial. In the present study, we aimed to clarify the prognostic impact of PIK3CA mutations in stage I-III CC according to...

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PMID: 25641861
DOI: 10.1002/cam4.370
PMCID: PMC4380963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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