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Article

Clinical Impact and Prognostic Role of KRAS/BRAF/PIK3CA Mutations in Stage I Colorectal Cancer.

Disease markers - 1 Jan 2018

Reggiani Bonetti Luca, Barresi Valeria, Maiorana Antonino, Manfredini Samantha, Caprera Cecilia, Bettelli Stefania

Abstract excerpt

Stage I colorectal carcinoma has excellent prognosis, with 5-year survival rate up to 95%. The occurrence of lymphovascular invasion, tumor budding, high number of PDC, or lymph node micrometastases is associated with tumor progression. The aim of this study was to evaluate the mutational status of 62 stage I colorectal carcinomas (CRC) (taken from 37 patients surviving more than five years since the initial...

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Source

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Identifiers

PMID: 30018674
DOI: 10.1155/2018/2959801
PMCID: PMC6029483

Genes

KRAS
BRAF
PDC
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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