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Article

Prognostic and Predictive Value of PIK3CA Mutations in Metastatic Colorectal Cancer.

Targeted oncology - 1 Jul 2022

Tan Elaine S, Fan Wenyi, Knepper Todd C, Schell Michael J, Sahin Ibrahim H, Fleming Jason B, Xie Hao

Abstract excerpt

BACKGROUND: Comprehensive genomic profiling is used to guide the management of metastatic colorectal cancer (mCRC); however, the role of PIK3CA mutations, present in up to 20% of mCRCs, is unclear. OBJECTIVE: This study aimed to evaluate the association of PIK3CA mutations with other common mutations in mCRC and determine the prognostic and predictive value of PIK3CA mutations. PATIENTS AND METHODS: A...

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PMID: 35767139
DOI: 10.1007/s11523-022-00898-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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