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Article

PIK3CA mutations predict local recurrences in rectal cancer patients.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Nov 2009

He Youji, Van't Veer Laura J, Mikolajewska-Hanclich Izabela, van Velthuysen Marie-Louise F, Zeestraten Eliane C M, Nagtegaal Iris D, van de Velde Cornelis J H, Marijnen Corrie A M

Abstract excerpt

PURPOSE: Identifying rectal cancer patients at risk for local recurrence would allow for refinement in the selection of patients who would benefit from preoperative radiotherapy. PIK3CA, KRAS, and BRAF mutations are commonly found in colon cancers, but their prevalence has not been clearly assess...

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Source

Identifiers

PMID: 19903786
DOI: 10.1158/1078-0432.CCR-09-1165

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19903786-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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