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Article

Genetic alterations of K-ras may reflect prognosis in stage III colon cancer patients below 60 years of age.

Journal of surgical oncology - 1 Jan 2011

Onozato Wataru, Yamashita Keishi, Yamashita Kazuya, Kuba Tatsuru, Katoh Hiroshi, Nakamura Takatoshi, Sato Takeo, Ihara Atsushi, Okayasu Isao, Watanabe Masahiko

Abstract excerpt

PURPOSE: Genetic alterations that are closely associated with patient prognosis can be landmarks of definitive therapeutic targets as well as useful biomarkers in human cancer clinics. METHODS: Three hundred seventy-eight colorectal cancer (CRC) patients were examined for K-ras mutations by single-strand conformation polymorphism (SSCP), with a subsequent 144 young colon cancer (YCC) patients added to validate...

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PMID: 21031422
DOI: 10.1002/jso.21710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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