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Article

Lipid abnormalities in alpha/beta2-syntrophin null mice are independent from ABCA1.

Biochimica et biophysica acta - 1 May 2015

Hebel Tobias, Eisinger Kristina, Neumeier Markus, Rein-Fischboeck Lisa, Pohl Rebekka, Meier Elisabeth M, Boettcher Alfred, Froehner Stanley C, Adams Marvin E, Liebisch Gerhard, Krautbauer Sabrina, Buechler Christa

Abstract excerpt

The syntrophins alpha (SNTA) and beta 2 (SNTB2) are molecular adaptor proteins shown to stabilize ABCA1, an essential regulator of HDL cholesterol. Furthermore, SNTB2 is involved in glucose stimulated insulin release. Hyperglycemia and dyslipidemia are characteristic features of the metabolic syndrome, a serious public health problem with rising prevalence. Therefore, it is important to understand the role of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25625330
DOI: 10.1016/j.bbalip.2015.01.012
PMCID: PMC4363173

Genes

ABCA1
SNTB2
PDZK1
NHERF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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