Article
Role of apoA-I, ABCA1, LCAT, and SR-BI in the biogenesis of HDL.
Journal of molecular medicine (Berlin, Germany) - 1 Apr 2006
Zannis Vassilis I, Chroni Angeliki, Krieger Monty
Abstract excerpt
The concentration, composition, shape, and size of plasma high-density lipoprotein (HDL) are determined by numerous proteins that influence its biogenesis, remodeling, and catabolism. The discoveries of the HDL receptor (scavenger receptor class B type I, SR-BI) and the ABCA1 (ATP-binding cassette transporter A1) lipid transporter provided two missing links that were necessary to understand the biogenesis and...
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