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Article

Interplay between cardiolipin and plasmalogens in Barth syndrome.

Journal of inherited metabolic disease - 1 Jan 2022

Bozelli José Carlos, Epand Richard M

Abstract excerpt

Barth syndrome (BTHS) is a rare inherited metabolic disease resulting from mutations in the gene of the enzyme tafazzin, which catalyzes the acyl chain remodeling of the mitochondrial-specific lipid cardiolipin (CL). Tissue samples of individuals with BTHS present abnormalities in the level and the molecular species of CL. In addition, in tissues of a tafazzin knockdown mouse as well as in cells derived from BTHS...

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Identifiers

PMID: 34655242
DOI: 10.1002/jimd.12449

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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