Article
The single nucleotide polymorphism and haplotype analysis of MDR1 in Jiangsu Han population of China.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Sept 2012
Qiu Hairong, Dong Huajie, Pan Shiyang, Miao Kourong
Abstract excerpt
The aim of this study was to perform the frequency distribution of MDR1 gene SNPs and haplotypes of Jiangsu Han population in China. A total of 225 Jiangsu Han unrelated volunteers were enrolled and genotyped by PCR-ASP method at three loci: C1236T (rs1128503), G2677T/A (rs2032582) and C3435T (rs1045642). In total, C and T were found at locus 1236, with the frequency of 35% and 65%, respectively. The most...
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