Article
Genetic variability and haplotype profile of MDR1 in Saudi Arabian males.
Molecular biology reports - 1 Dec 2012
Al-Mohizea Abdullah M, Alkharfy Khalid M, Bagulb Khawla M, Alghamdi Amal M, Al-Jenoobi Fahad I, Al-Muhsen Saleh, Halwani Rabih, Parvez Mohammad Khalid, Khalid Parvez M, Al-Dosari Mohammed S
Abstract excerpt
Polymorphisms in multidrug resistance (MDR1) gene play an important role in influencing the pharmacological action and toxicity profile of a large number of therapeutic agents, and in human susceptibility to various diseases. Because of genotypic variability, several studies were directed toward determination of the frequencies of MDR1 polymorphisms and/or haplotypes in different ethnic populations. In this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
