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Article

Simultaneous analysis of MDR1 C3435T, G2677T/A, and C1236T genotypes by multiplexed mutagenically separated PCR.

Clinical chemistry and laboratory medicine - 1 Jan 2005

Sunder-Plassmann Raute, Rieger Sandra, Endler Georg, Brunner Martin, Müller Markus, Mannhalter Christine

Abstract excerpt

P-glycoprotein (PGP) encoded by the multi-drug-resistance 1 (MDR1) gene is a member of the ATP-binding cassette (ABC) transporter family, drug-transporting proteins involved in the bioavailability and pharmacokinetics of various drugs. Several single nucleotide polymorphisms (SNPs) in the MDR1 gene have been identified so far that may influence PGP expression levels and function. Thus, genotyping for MDR1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15843215
DOI: 10.1515/CCLM.2005.032

Genes

PGP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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