Frequency of the three most common polymorphisms in the MDR1 gene in Slovak population.

Abstract excerpt

UNLABELLED: The human multidrug resistance gene (<em>MDR1</em>) is encoding the transmembrane transporter P-glycoprotein (P-gp) which plays an important role in the efflux of various drugs and thus is potentially influencing the drug-treatment outcome. It has been indicated that the level of P-gp activity may be affected by the presence of single nucleotide polymorphisms (SNP) in the gene which led to the studies...

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