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Article

Reduced expression of the MDA5 Gene IFIH1 prevents autoimmune diabetes.

Diabetes - 1 Jun 2015

Lincez Pamela J, Shanina Iryna, Horwitz Marc S

Abstract excerpt

Although it is widely accepted that type 1 diabetes (T1D) is the result of the autoimmune destruction of insulin-producing β-cells in the pancreas, little is known about the events leading to islet autoimmunity. Epidemiological and genetic data have associated virus infections and antiviral type I interferon (IFN-I) response genes with T1D. Genetic variants in the T1D risk locus interferon induced with helicase C...

Read the complete abstract on PubMed

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Share to DEAD-box RNA Helicases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Immunohistochemistry

Share to Interferon-Induced Helicase, IFIH1

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Source

Identifiers

PMID: 25591872
DOI: 10.2337/db14-1223

Genes

IFIH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Reduced expression of the MDA5 Gene IFIH1 prevents autoimmune diabetes.PMID 25591872Read ↗

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