Article
Skin reaction and regeneration after single sodium lauryl sulfate exposure stratified by filaggrin genotype and atopic dermatitis phenotype.
The British journal of dermatology - 1 Jun 2015
Bandier J, Carlsen B C, Rasmussen M A, Petersen L J, Johansen J D
Abstract excerpt
BACKGROUND: Filaggrin is key for the integrity of the stratum corneum. Mutations in the filaggrin gene (FLGnull) play a prominent role in atopic dermatitis (AD) pathogenesis. People with AD have increased susceptibility to irritants. However, little is known about the effect of filaggrin genotype and AD phenotype on irritant response and skin regeneration. OBJECTIVES: To investigate the role of FLGnull and AD...
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