Article
Toward a major risk factor for atopic eczema: meta-analysis of filaggrin polymorphism data.
The Journal of allergy and clinical immunology - 1 Dec 2007
Baurecht Hansjörg, Irvine Alan D, Novak Natalija, Illig Thomas, Bühler Bettina, Ring Johannes, Wagenpfeil Stefan, Weidinger Stephan
Abstract excerpt
BACKGROUND: With an impressive series of replication studies, filaggrin (FLG) has become the gene with the most widely replicated association to atopic eczema (AE). However, studies published to date demonstrate differences concerning study design and strength of associations. OBJECTIVES: We sought to provide a general and overall estimate of FLG effect sizes and to estimate allele and carrier frequencies....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.