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Article

Distinct barrier integrity phenotypes in filaggrin-related atopic eczema following sequential tape stripping and lipid profiling.

Experimental dermatology - 1 Apr 2011

Angelova-Fischer Irena, Mannheimer Anna-Clara, Hinder Anke, Ruether Andreas, Franke Andre, Neubert Reinhard H H, Fischer Tobias W, Zillikens Detlef

Abstract excerpt

BACKGROUND: Filaggrin gene (FLG) loss-of-function mutations have been shown to represent the strongest so far known genetic risk factor for atopic dermatitis (AD). Whereas the barrier characteristics in FLG mutation carriers under baseline conditions have been investigated, there are only limited data on the permeability barrier function in filaggrin-AD under compromised conditions. AIM: We investigated: (i)...

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Source

Identifiers

PMID: 21410766
DOI: 10.1111/j.1600-0625.2011.01259.x

Genes

FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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