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Article

Genetic Basis of Irritant Susceptibility in Health Care Workers.

Journal of occupational and environmental medicine - 1 Aug 2016

Yucesoy Berran, Talzhanov Yerkebulan, Barmada M Michael, Johnson Victor J, Kashon Michael L, Baron Elma, Wilson Nevin W, Frye Bonnie, Wang Wei, Fluharty Kara, Gharib Rola, Meade Jean, Germolec Dori, Luster Michael I, Nedorost Susan

Abstract excerpt

OBJECTIVE: The aim of this study was to investigate the association of single nucleotide polymorphisms (SNPs) within genes involved in inflammation, skin barrier integrity, signaling/pattern recognition, and antioxidant defense with irritant susceptibility in a group of health care workers. METHODS: The 536 volunteer subjects were genotyped for selected SNPs and patch tested with three model irritants: sodium...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27206134
DOI: 10.1097/JOM.0000000000000784
PMCID: PMC4980183

Genes

ACACB
EGFR
PLAU
CXCL12
EGF
FGF2
NTRK2
NTRK3
VCAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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