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Article

The population genetics of dN/dS.

PLoS genetics - 1 Dec 2008

Kryazhimskiy Sergey, Plotkin Joshua B

Abstract excerpt

Evolutionary pressures on proteins are often quantified by the ratio of substitution rates at non-synonymous and synonymous sites. The dN/dS ratio was originally developed for application to distantly diverged sequences, the differences among which represent substitutions that have fixed along in...

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Identifiers

PMID: 19081788
DOI: 10.1371/journal.pgen.1000304
PMCID: PMC2596312

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19081788-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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